Infection with Liver Flukes
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چکیده
of hepatic aflatoxIn Bi and N-nitrosodiethylamine in infected males and 20-40% in infected females (Kirby et al., 1994). Immunohistochemical analysis of aflatoxIn Bi-DNA adducts in parasitized animaIs indicated that the greatest numbers of adducts occurred in the regions of highest CYP2A activity. Studies with a related liver fluke, Fasciola hepatica, also showed enhanced cyochrome P450-related activation of aflatoxIn Bi into a mutagen by liver extracts from fluke-infected mice over that with extracts prepared from livers of uninfected animais
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Flukes liver epidemic common between human and livestock in slaughtered and their staining
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